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Is this test appropriate for me?

It’s a simple saliva test you can do from home. It looks at millions of common genetic variants and how they affect your risk of common conditions.

Keep in mind:

  • This test uses your genetics, sex, ethnicity and other clinical factors to estimate your risk of common health conditions. This estimate may additionally include other risk factors such as QRISK®3 and QDiabetes®-2018.
  • Other things, like lifestyle, environment, personal and family medical history, also affect your risk. The test does not take into account all the factors that affect your risk.
  • The test does not look at all possible genetic variants linked to each condition. For example, it does not look at rare genetic variants.
  • In the laboratory, we analyse your DNA using a tool called a genotyping array. In very rare cases, an individual’s health history can affect the genotyping accuracy. Examples include certain cancers, allogeneic bone marrow transplant, blood transfusions within 7 days of testing, and chemotherapy
    within 120 days of testing.
For each condition, we combine the effects of millions of variants into a score. This is called a polygenic risk score or PRS. The performance of the polygenic risk score varies across different ancestry groups due to the availability of data used to train the scores. Genomics have developed powerful methodologies to minimise ancestry-related biases in polygenic risk scores, but even with this predictive power is not equal in all populations.